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Article

Conformation analysis of a surface loop that controls active site access in the GH11 xylanase A from Bacillus subtilis.

Journal of molecular modeling - 1 Apr 2012

Vieira Davi Serradella, Ward Richard John

Abstract excerpt

Xylanases (EC 3.2.1.8 endo-1,4-glycosyl hydrolase) catalyze the hydrolysis of xylan, an abundant hemicellulose of plant cell walls. Access to the catalytic site of GH11 xylanases is regulated by movement of a short β-hairpin, the so-called thumb region, which can adopt open or closed conformations. A crystallographic study has shown that the D11F/R122D mutant of the GH11 xylanase A from Bacillus subtilis (BsXA)...

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Source

Identifiers

PMID: 21785938
DOI: 10.1007/s00894-011-1172-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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