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Article

Association of HFE and TMPRSS6 genetic variants with iron and erythrocyte parameters is only in part dependent on serum hepcidin concentrations.

Journal of medical genetics - 1 Sept 2011

Traglia Michela, Girelli Domenico, Biino Ginevra, Campostrini Natascia, Corbella Michela, Sala Cinzia, Masciullo Corrado, Viganò Fiammetta, Buetti Iwan, Pistis Giorgio, Cocca Massimiliano, Camaschella Clara, Toniolo Daniela

Abstract excerpt

BACKGROUND: Hepcidin is the main regulator of iron homeostasis: inappropriate production of hepcidin results in iron overload or iron deficiency and anaemia. AIMS: To study variation of serum hepcidin concentration in a normal population. RESULTS: Hepcidin showed age and sex dependent variations that correlated with ferritin but not with serum iron and transferrin saturation. The size of the study population was...

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Share to Antimicrobial Cationic Peptides
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Histocompatibility Antigens Class I

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Source

Identifiers

PMID: 21785125
DOI: 10.1136/jmedgenet-2011-100061

Genes

HFE
TMPRSS6

Variants

rs1800562

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Association of HFE and TMPRSS6 genetic variants with iron and erythrocyte parameters is only in part dependent on serum hepcidin concentrations.PMID 21785125Read ↗

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