Article
Pabp binds to the osk 3'UTR and specifically contributes to osk mRNA stability and oocyte accumulation.
Developmental biology - 15 Sept 2011
Vazquez-Pianzola Paula, Urlaub Henning, Suter Beat
Abstract excerpt
RNA localization is tightly coordinated with RNA stability and translation control. Bicaudal-D (Bic-D), Egalitarian (Egl), microtubules and their motors are part of a Drosophila transport machinery that localizes mRNAs to specific cellular regions during oogenesis and embryogenesis. We identified the Poly(A)-binding protein (Pabp) as a protein that forms an RNA-dependent complex with Bic-D in embryos and ovaries....
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