Article
Cell Death Pathways in Mutant Rhodopsin Rat Models Identifies Genotype-Specific Targets Controlling Retinal Degeneration.
Molecular neurobiology - 1 Mar 2019
Viringipurampeer Ishaq A, Gregory-Evans Cheryl Y, Metcalfe Andrew L, Bashar Emran, Moritz Orson L, Gregory-Evans Kevin
Abstract excerpt
Retinitis pigmentosa (RP) is a group of inherited neurological disorders characterized by rod photoreceptor cell death, followed by secondary cone cell death leading to progressive blindness. Currently, there are no viable treatment options for RP. Due to incomplete knowledge of the molecular signaling pathways associated with RP pathogenesis, designing therapeutic strategies remains a challenge. In particular,...
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