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Article

Rab38 targets to lamellar bodies and normalizes their sizes in lung alveolar type II epithelial cells.

American journal of physiology. Lung cellular and molecular physiology - 1 Oct 2011

Zhang Linghui, Yu Kevin, Robert Kyle W, DeBolt Kristine M, Hong Nankang, Tao Jian-Qin, Fukuda Mitsunori, Fisher Aron B, Huang Shaohui

Abstract excerpt

Rab38 is a rat Hermansky-Pudlak syndrome gene that plays an important role in surfactant homeostasis in alveolar type II (ATII) pneumocytes. We examined Rab38 function in regulating lamellar body (LB) morphology in ATII cells. Quantitative electron microscopy revealed that LBs in ATII cells were ∼77% larger in Rab38-null fawn-hooded hypertension (FHH) than control Sprague-Dawley (SD) rats. Rab38 protein...

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Share to Alveolar Epithelial Cells
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Pulmonary Alveoli

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Identifiers

PMID: 21764986
DOI: 10.1152/ajplung.00056.2011
PMCID: PMC3191760

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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