Article
Role of P27 -P55 operon from Mycobacterium tuberculosis in the resistance to toxic compounds.
BMC infectious diseases - 16 Jul 2011
Bianco María V, Blanco Federico C, Imperiale Belén, Forrellad Marina A, Rocha Roxana V, Klepp Laura I, Cataldi Angel A, Morcillo Nora, Bigi Fabiana
Abstract excerpt
BACKGROUND: The P27-P55 (lprG-Rv1410c) operon is crucial for the survival of Mycobacterium tuberculosis, the causative agent of human tuberculosis, during infection in mice. P55 encodes an efflux pump that has been shown to provide Mycobacterium smegmatis and Mycobacterium bovis BCG with resistance to several drugs, while P27 encodes a mannosylated glycoprotein previously described as an antigen that modulates...
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