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Article

Cell population heterogeneity in Mycobacterium tuberculosis H37Rv.

Tuberculosis (Edinburgh, Scotland) - 1 Nov 2008

Andreu Núria, Gibert Isidre

Abstract excerpt

The laboratory strain H37Rv represents one of the most commonly used strains in the study of Mycobacterium tuberculosis. Despite the apparent stability of the strain, the absence of a selective pressure for virulence factors could lead to the in vitro accumulation of attenuated mutants. To assess this hypothesis, we performed a systematic analysis of individual clones isolated from subcultured M. tuberculosis...

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Identifiers

PMID: 18502178
DOI: 10.1016/j.tube.2008.03.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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