Article
Differential MHC class I expression in distinct leukocyte subsets.
BMC immunology - 15 Jul 2011
Greene Justin M, Wiseman Roger W, Lank Simon M, Bimber Benjamin N, Karl Julie A, Burwitz Benjamin J, Lhost Jennifer J, Hawkins Oriana E, Kunstman Kevin J, Broman Karl W, Wolinsky Steven M, Hildebrand William H, O'Connor David H
Abstract excerpt
BACKGROUND: MHC class I proteins are partly responsible for shaping the magnitude and focus of the adaptive cellular immune response. In humans, conventional wisdom suggests that the HLA-A, -B, and -C alleles are equally expressed on the majority of cell types. While we currently have a thorough understanding of how total MHC class I expression varies in different tissues, it has been difficult to examine...
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