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Article

TLR4 in skin cancer: From molecular mechanisms to clinical interventions

24 Apr 2019

Abstract excerpt

The health and economic burden imposed by skin cancer is substantial, creating an urgent need for the development of improved molecular strategies for its prevention and treatment. Cutaneous exposure to solar ultraviolet (UV) radiation is a causative factor in skin carcinogenesis, and TLR4-dependent inflammatory dysregulation is an emerging key mechanism underlying detrimental effects of acute and chronic UV...

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Immune Response and Inflammation
NF-κB Signaling Pathways
Skin Protection and Aging

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31020719
DOI: 10.1002/mc.23016

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