Article
The angiotensinogen gene of Swiss mice is closely linked to a retrovirus-like element.
DNA and cell biology - 1 Nov 1990
Clouston W M
Abstract excerpt
Angiotensinogen is cleaved by renin and angiotensin-converting enzyme to liberate the potent vasocontrictor peptide angiotensin II. We have recently identified a cis-acting genetic lesion associated with high levels of angiotensinogen mRNA in the testis and salivary gland of Swiss mice. To determine the molecular basis of this mutation, the Swiss angiotensinogen gene was cloned, and its structure was compared to...
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