Article
Genetic mapping of the athymic nude (RNU) locus in the rat to a region on chromosome 10.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1993
Cash J M, Remmers E F, Goldmuntz E A, Crofford L J, Zha H, Hansen C T, Wilder R L
Abstract excerpt
The nude trait in the rat is transmitted in an autosomal recessive manner and is associated with thymic aplasia, T-cell deficiency, and hairlessness. Congenic rats homozygous for the RNU (Rowett nude) locus are important models in the study of inflammatory disease, tumor growth, and transplant rejection. The RNU locus has not been previously mapped, and the nature of the gene product is unknown. To determine the...
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