Article
Genetic mapping of the athymic nude (RNU) locus in the rat to a region on chromosome 10.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1993
Cash J M, Remmers E F, Goldmuntz E A, Crofford L J, Zha H, Hansen C T, Wilder R L
Abstract excerpt
The nude trait in the rat is transmitted in an autosomal recessive manner and is associated with thymic aplasia, T-cell deficiency, and hairlessness. Congenic rats homozygous for the RNU (Rowett nude) locus are important models in the study of inflammatory disease, tumor growth, and transplant re...
Topics
- Animals
- Base Sequence
- Chromosome Mapping
- Female
- Genetic Linkage
- Genotype
- Male
- Molecular Sequence Data
- Oligonucleotide Probes
- Phenotype
- Rats
- Rats, Inbred F344
- Rats, Inbred Lew
- Rats, Nude