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Article

SNPing at the Epidermal Barrier.

The Journal of investigative dermatology - 1 Aug 2011

Kelsell David P, Byrne Carolyn

Abstract excerpt

Filaggrin variants are well-established risk factors for atopic eczema (AE). Recent studies suggest additional epidermal differentiation complex (EDC) gene associations with AE. In this issue, Marenholz and colleagues confirm this prediction and show that a small proline-rich protein 3 (SPRR3) variant confers susceptibility to AE. This finding suggests that further genetic and functional characterization of SPRR3...

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Source

Identifiers

PMID: 21753762
DOI: 10.1038/jid.2011.92

Genes

SPRR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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