Characterization of Helicobacter pylori cagA and vacA genotypes among Alaskans and their correlation with clinical disease.

doi:10.1128/JCM.00469-11

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Article

Characterization of Helicobacter pylori cagA and vacA genotypes among Alaskans and their correlation with clinical disease.

Journal of clinical microbiology - 1 Sept 2011

Miernyk Karen, Morris Julie, Bruden Dana, McMahon Brian, Hurlburt Debby, Sacco Frank, Parkinson Alan, Hennessy Thomas, Bruce Michael

Abstract excerpt

Helicobacter pylori infection is common in Alaska. The development of severe H. pylori disease is partially determined by the virulence of the infecting strain. Here we present vacA and cagA genotype data for H. pylori strains isolated from Alaskans and their correlation with clinical disease. We enrolled patients scheduled for esophagogastroduodenoscopy and positive for H. pylori infection. Gastric biopsy...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Alaska
Antigens, Bacterial
Bacterial Proteins
Biopsy
Esophagitis
Female
Gastric Mucosa

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Helicobacter Infections

Helicobacter pylori

Humans

Male

Middle Aged

Peptic Ulcer

Source

Open in PubMed Open full text

Identifiers

PMID: 21752979
DOI: 10.1128/JCM.00469-11
PMCID: PMC3165571

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-21752979-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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