Article
The importance of vacA, cagA, and iceA genotypes of Helicobacter pylori infection in peptic ulcer disease and gastroesophageal reflux disease.
The American journal of gastroenterology - 1 Sept 2001
Arents N L, van Zwet A A, Thijs J C, Kooistra-Smid A M, van Slochteren K R, Degener J E, Kleibeuker J H, van Doorn L J
Abstract excerpt
OBJECTIVE: To study the relationship between the presence of H. pylori virulence factors and clinical outcome in H. pylori infected patients. METHODS: DNA was isolated from an antral biopsy sample and vacA, cagA, and iceA genotype were determined by PCR and a reverse hybridization technique in 183 patients with culture-proven H. pylori infection: 51 with peptic ulcer disease (PUD), 62 with gastroesophageal reflux...
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