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Article

Regulation of Caenorhabditis elegans vitellogenesis by DAF-2/IIS through separable transcriptional and posttranscriptional mechanisms.

BMC physiology - 12 Jul 2011

DePina Ana S, Iser Wendy B, Park Sung-Soo, Maudsley Stuart, Wilson Mark A, Wolkow Catherine A

Abstract excerpt

BACKGROUND: Evolutionary theories of aging propose that longevity evolves as a competition between reproduction and somatic maintenance for a finite pool of resources. Reproduction is thought to shorten lifespan by depleting resources from processes promoting somatic maintenance. Maternal yolk production, vitellogenesis, represents a significant maternal cost for reproduction and is suppressed under genetic and...

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Identifiers

PMID: 21749693
DOI: 10.1186/1472-6793-11-11
PMCID: PMC3160409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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