Interleukin 4-590T/C polymorphism and susceptibility to leprosy.

doi:10.1089/gtmb.2011.0032

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Article

Interleukin 4-590T/C polymorphism and susceptibility to leprosy.

Genetic testing and molecular biomarkers - 1 Dec 2011

Yang Degang, Song Haihan, Xu Weimin, Long Heng, Shi Chao, Jing Zhichun, Song Weiguo, Pei Bin

Abstract excerpt

BACKGROUND: Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Cell-mediated (Th1) immune response and humoral (Th2) immune response play different roles in leprosy infection. Interleukin 4 (IL-4) is a typical Th2 cytokine. It is a critical mediator of the Th1/Th2 balance. OB...

Topics

Adolescent
Adult
Asian People
Case-Control Studies
Child
Child, Preschool
Female
Genetic Predisposition to Disease
Humans
Infant
Infant, Newborn
Interleukin-4
Leprosy
Male
Middle Aged
Polymerase Chain Reaction
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 21749213
DOI: 10.1089/gtmb.2011.0032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-21749213-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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