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Article

Interleukin 4-590T/C polymorphism and susceptibility to leprosy.

Genetic testing and molecular biomarkers - 1 Dec 2011

Yang Degang, Song Haihan, Xu Weimin, Long Heng, Shi Chao, Jing Zhichun, Song Weiguo, Pei Bin

Abstract excerpt

BACKGROUND: Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Cell-mediated (Th1) immune response and humoral (Th2) immune response play different roles in leprosy infection. Interleukin 4 (IL-4) is a typical Th2 cytokine. It is a critical mediator of the Th1/Th2 balance. OBJECTIVE: The objective of this study is to investigate the association between IL-4 gene -590T/C polymorphism and the...

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Identifiers

PMID: 21749213
DOI: 10.1089/gtmb.2011.0032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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