IL-4 -590C/T polymorphism and susceptibility to liver disease: a meta-analysis and meta-regression.

doi:10.1089/dna.2013.2020

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Article

IL-4 -590C/T polymorphism and susceptibility to liver disease: a meta-analysis and meta-regression.

DNA and cell biology - 1 Aug 2013

Zheng Zhen, Li Xu, Li Zhiliang, Ma Xiao-Chun

Abstract excerpt

Interleukin-4 (IL-4) is a pleiotropic cytokine that plays an important role in the immune system. Emerging evidences have shown that the common polymorphism (-590C/T; rs2243250 C>T) in the IL-4 gene may play an important role in the development of various liver diseases, but individually publishe...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Algorithms
Case-Control Studies
Female
Genetic Association Studies
Genetic Predisposition to Disease
Hepatitis B
Hepatitis C
Humans
Interleukin-4
Liver Diseases
Male
Middle Aged
Polymorphism, Single Nucleotide
Regression Analysis

Source

Open in PubMed

Identifiers

PMID: 23768103
DOI: 10.1089/dna.2013.2020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-23768103-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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