Article
Phenotype pharmacology of lower urinary tract α(1)-adrenoceptors.
British journal of pharmacology - 1 Mar 2012
Nishimune A, Yoshiki H, Uwada J, Anisuzzaman A S M, Umada H, Muramatsu I
Abstract excerpt
α(1)-Adrenoceptors are involved in numerous physiological functions, including micturition. However, the pharmacological profile of the α(1)-adrenoceptor subtypes remains controversial. Here, we review the literature regarding α(1)-adrenoceptors in the lower urinary tract from the standpoint of α(1L) phenotype pharmacology. Among three α(1)-adrenoceptor subtypes (α(1A), α(1B) and α(1D)), α(1a)-adrenoceptor mRNA...
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