Article
Alpha 1a-adrenoceptor polymorphism: pharmacological characterization and association with benign prostatic hypertrophy.
British journal of pharmacology - 1 Jul 1996
Shibata K, Hirasawa A, Moriyama N, Kawabe K, Ogawa S, Tsujimoto G
Abstract excerpt
1. Two restriction fragment length polymorphisms of the human alpha 1a-adrenoceptor gene digested with PstI restriction enzyme exist; the nucleotide change causes the substitution of C residue for T at nucleotide 1441, thereby Arg492 to Cys492 transition, which might confer an additional putative...
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