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Article

Increased gene copy number of ERG on chromosome 21 but not TMPRSS2-ERG fusion predicts outcome in prostatic adenocarcinomas.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Nov 2011

Toubaji Antoun, Albadine Roula, Meeker Alan K, Isaacs William B, Lotan Tamara, Haffner Michael C, Chaux Alcides, Epstein Jonathan I, Han Misop, Walsh Patrick C, Partin Alan W, De Marzo Angelo M, Platz Elizabeth A, Netto George J

Abstract excerpt

The role of TMPRSS2-ERG gene fusion in prostate cancer prognostication remains controversial. We evaluated the prognostic role of TMPRSS2-ERG fusion using fluorescence in situ hybridization analysis in a case-control study nested in The Johns Hopkins retropubic radical prostatectomy cohort. In all, 10 tissue microarrays containing paired tumors and normal tissues obtained from 172 cases (recurrence) and 172...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21743434
DOI: 10.1038/modpathol.2011.111
PMCID: PMC3360950

Genes

ERG
TMPRSS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Increased gene copy number of ERG on chromosome 21 but not TMPRSS2-ERG fusion predicts outcome in prostatic adenocarcinomas.PMID 21743434Read ↗

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