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Article

Mutation analysis of PINK1 gene in patients with early-onset Parkinsonism.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 1 Jun 2011

Zhang Xuewei, Zhang Hainan, Liao Bing, Guo Jifeng, Xia Kun, Tang Beisha

Abstract excerpt

OBJECTIVE: To determine the frequency of mutations in PINK1 in Chinese Han people with sporadic early-onset Parkinsonism (EOP). METHODS: DNA sequencing was used to detect point mutations and small deletions/insertions, and quantitative real-time PCR was carried out to detect deletions/insertions and rearrangements in 149 patients and 150 healthy controls. RESULTS: Four heterozygous mutations in PINK1 were...

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Source

Identifiers

PMID: 21743139
DOI: 10.3969/j.issn.1672-7347.2011.06.004

Genes

PINK1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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