Article
A common A340T variant in PINK1 gene associated with late-onset Parkinson's disease in Chinese.
Neuroscience letters - 20 Dec 2006
Wang Feng, Feng Xiuli, Ma Jinhong, Zou Haiqiang, Chan Piu
Abstract excerpt
Parkinson's disease (PD) is a complex neurodegenerative disease with genetic risk factors. Common variants in genes implicated in hereditary forms of parkinsonism may be predisposing factors for sporadic PD. Recent studies have demonstrated that mutations in PINK1 (PARK6 locus) gene, encoding PTEN-induced kinase 1, are associated with both familial recessive and sporadic early onset parkinsonism. In order to...
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