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Article

Evaluation of proteoglycan gene polymorphisms as risk factors in the genetic susceptibility to high myopia.

Investigative ophthalmology & visual science - 16 Aug 2011

Yip Shea Ping, Leung Kim Hung, Ng Po Wah, Fung Wai Yan, Sham Pak Chung, Yap Maurice K H

Abstract excerpt

PURPOSE. To investigate the relationship between high myopia and single nucleotide polymorphisms (SNPs) in six proteoglycan genes: aggrecan (ACAN), fibromodulin (FMOD), decorin (DCN), lumican (LUM), keratocan (KERA), and epiphycan (EPYC). These genes were selected for study because they are involved in induced myopia in animals and/or are within the human MYP3 locus identified by linkage analysis of families with...

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Identifiers

PMID: 21743019
DOI: 10.1167/iovs.11-7639

Genes

ACAN
DCN
EPYC
FMOD
KERA
LUM

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