Blockage to exonuclease III digestion in the chromatin of Saccharomyces cerevisiae maps to the in vitro--determined binding site of a trans-acting regulatory factor.

doi:10.1007/BF00321110

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Article

Blockage to exonuclease III digestion in the chromatin of Saccharomyces cerevisiae maps to the in vitro--determined binding site of a trans-acting regulatory factor.

Current genetics - 1 Jul 1990

Feaver W J, Pearlman R E

Abstract excerpt

A series of transposable element-induced mutations at the HIS4 locus in Saccharomyces cerevisiae have been attributed to the transposition of a Ty element into the 5' regulatory region of this gene. Various Ty-containing His+ revertants have been isolated and the HIS4/Ty junction region sequenced...

Topics

Binding Sites
Chromatin
DNA Transposable Elements
Deoxyribonuclease I
Exodeoxyribonucleases
Methylation
Mutation
Restriction Mapping
Saccharomyces cerevisiae
Trans-Activators

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