Article
A variant near the melanocortin-4 receptor gene regulates postprandial lipid metabolism in a healthy Caucasian population.
The British journal of nutrition - 1 Aug 2011
Perez-Martinez Pablo, Garcia-Rios Antonio, Delgado-Lista Javier, Delgado-Casado Nieves, Malagon Maria M, Marin Carmen, Gomez-Luna Purificacion, Caballero Javier, Perez-Jimenez Francisco, Lopez-Miranda Jose
Abstract excerpt
The melanocortin-4 receptor (MC4R) is an essential regulator of food intake and energy homeostasis. Previous data suggest an influence of MC4R activity on TAG levels. Thus, the aim of the present study was to determine whether the presence of the rs12970134 polymorphism near the MC4R gene could influence postprandial lipoprotein metabolism in healthy subjects. A total of eighty-eight volunteers were selected,...
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