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Article

An Association between Diet and MC4R Genetic Polymorphism, in Relation to Obesity and Metabolic Parameters-A Cross Sectional Population-Based Study.

International journal of molecular sciences - 7 Nov 2021

Adamska-Patruno Edyta, Bauer Witold, Bielska Dorota, Fiedorczuk Joanna, Moroz Monika, Krasowska Urszula, Czajkowski Przemyslaw, Wielogorska Marta, Maliszewska Katarzyna, Puckowska Sylwia, Szczerbinski Lukasz, Lipinska Danuta, Gorska Maria, Kretowski Adam

Abstract excerpt

The melanocortin-4 receptor (MC4R) gene harbours one of the strongest susceptibility loci for obesity and obesity-related metabolic consequences. We analysed whether dietary factors may attenuate the associations between MC4R genotypes and obesity and metabolic parameters. In 819 participants genotyped for common MC4R polymorphisms (rs17782313, rs12970134, rs633265, and rs135034), the anthropometric measurements,...

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Adolescent
Adult
Aged
Cardiometabolic Risk Factors
Cross-Sectional Studies
Diet
Energy Metabolism
Female
Gene-Environment Interaction
Genetic Association Studies
Genetic Predisposition to Disease
Genotype
Humans
Male
Metabolic Diseases
Middle Aged
Obesity
Poland

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Identifiers

PMID: 34769477
DOI: 10.3390/ijms222112044
PMCID: PMC8584592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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An Association between Diet and MC4R Genetic Polymorphism, in Relation to Obesity and Metabolic Parameters-A Cross Sectional Population-Based Study.PMID 34769477Read ↗

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