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Article

A comparative analysis of DNA methylation across human embryonic stem cell lines.

Genome biology - 6 Jul 2011

Chen Pao-Yang, Feng Suhua, Joo Jong Wha Joanne, Jacobsen Steve E, Pellegrini Matteo

Abstract excerpt

BACKGROUND: We performed a comparative analysis of the genome-wide DNA methylation profiles from three human embryonic stem cell (HESC) lines. It had previously been shown that HESC lines had significantly higher non-CG methylation than differentiated cells, and we therefore asked whether these sites were conserved across cell lines. RESULTS: We find that heavily methylated non-CG sites are strongly conserved,...

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Identifiers

PMID: 21733148
DOI: 10.1186/gb-2011-12-7-r62
PMCID: PMC3218824

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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