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Article

A mouse model of the aniridia-Wilms tumor deletion syndrome.

Science (New York, N.Y.) - 9 Nov 1990

Glaser T, Lane J, Housman D

Abstract excerpt

Deletion of chromosome 11p13 in humans produces the WAGR syndrome, consisting of aniridia (an absence or malformation of the iris), Wilms tumor (nephroblastoma), genitourinary malformations, and mental retardation. An interspecies backcross between Mus musculus/domesticus and Mus spretus was made in order to map the homologous chromosomal region in the mouse genome and to define an animal model of this syndrome....

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Identifiers

PMID: 2173141
DOI: 10.1126/science.2173141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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