Location of the gene involving the small eye mutation on mouse chromosome 2 suggests homology with human aniridia 2 (AN2).

doi:10.1016/0888-7543(90)90550-e

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Article

Location of the gene involving the small eye mutation on mouse chromosome 2 suggests homology with human aniridia 2 (AN2).

Genomics - 1 Jun 1990

van der Meer-de Jong R, Dickinson M E, Woychik R P, Stubbs L, Hetherington C, Hogan B L

Abstract excerpt

Using an interspecific backcross, we have mapped the gene involved in the mouse Small eye mutation (SeyMH) relative to six cloned markers on chromosome 2 (Hox-5.1, Cas-1, Fshb, Bmp-2a, and ld) and the agouti locus. The results suggest that the Sey gene maps between Fshb and Cas-1. Human mapping s...

Topics

Animals
Aniridia
Chromosome Mapping
Chromosomes
Crosses, Genetic
Eye Abnormalities
Female
Genes
Humans
Male
Mice
Mice, Inbred C57BL
Mutation
Sequence Homology, Nucleic Acid

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