Article
Novel genotyping and quantitative analysis of neuraminidase inhibitor resistance-associated mutations in influenza a viruses by single-nucleotide polymorphism analysis.
Antimicrobial agents and chemotherapy - 1 Oct 2011
Duan Susu, Boltz David A, Li Jiang, Oshansky Christine M, Marjuki Henju, Barman Subrata, Webby Richard J, Webster Robert G, Govorkova Elena A
Abstract excerpt
Neuraminidase (NA) inhibitors are among the first line of defense against influenza virus infection. With the increased worldwide use of the drugs, antiviral susceptibility surveillance is increasingly important for effective clinical management and for public health epidemiology. Effective monitoring requires effective resistance detection methods. We have developed and validated a novel genotyping method for...
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