Article
Detection of H275Y oseltamivir resistance gene mutation among Influenza A(H1N1)pdm09 patients by allelic discrimination real-time RT-PCR.
Journal of medical virology - 1 May 2023
Krishna Smriti, Jayaram Anup, Shetty Ujwal, Varamballi Prasad, Mukhopadhyay Chiranjay, Jagadesh Anitha
Abstract excerpt
Influenza viruses can mutate genetically and cause a range of respiratory ailments. The H275Y mutation in the neuraminidase (NA) gene reduces the effectiveness of oseltamivir, a widely used drug for the treatment of Influenza A and B virus infection. The World Health Organization (WHO) recommends single-nucleotide polymorphism assays to detect this mutation. The present study aims to estimate the prevalence of...
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