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Article

Detection of antiviral resistance and genetic lineage markers in influenza B virus neuraminidase using pyrosequencing.

Antiviral research - 1 Feb 2010

Sheu Tiffany G, Deyde Varough M, Garten Rebecca J, Klimov Alexander I, Gubareva Larisa V

Abstract excerpt

We report here the design of a pyrosequencing approach for the detection of molecular markers of resistance to the neuraminidase inhibitors zanamivir and oseltamivir in influenza viruses of type B. Primers were designed to analyze the sequences at eight amino acid positions E119, R152, D198, I222, S250, H274, R371, and G402 (universal A/N2 numbering) in the neuraminidase (NA) which have been previously found to...

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Source

Identifiers

PMID: 19887086
DOI: 10.1016/j.antiviral.2009.10.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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