Article
Sox factors transcriptionally regulate ROBO4 gene expression in developing vasculature in zebrafish.
The Journal of biological chemistry - 2 Sept 2011
Samant Ganesh V, Schupp Marcus O, François Mathias, Moleri Silvia, Kothinti Rajendra K, Chun Chang Zoon, Sinha Indranil, Sellars Suzanna, Leigh Noah, Pramanik Kallal, Horswill Mark A, Remadevi Indulekha, Li Keguo, Wilkinson George A, Tabatabai Niloofar M, Beltrame Monica, Koopman Peter, Ramchandran Ramani
Abstract excerpt
Despite their importance as members of the Roundabout (Robo) family in the control of axonal and vascular patterning, the transcriptional regulation of these genes is poorly understood. In this study, we show that members of the Sry-related high mobility box (Sox) transcription factor family as being transcriptional regulators of roundabout4 (robo4), a Robo gene family member that participates in sprouting...
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