Article
Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men.
The Journal of nutrition - 1 May 2012
Major Jacqueline M, Yu Kai, Chung Charles C, Weinstein Stephanie J, Yeager Meredith, Wheeler William, Snyder Kirk, Wright Margaret E, Virtamo Jarmo, Chanock Stephen, Albanes Demetrius
Abstract excerpt
Vitamin E inhibits lipid peroxidation in cell membranes, prevents oxidative damage to DNA by scavenging free radicals, and reduces carcinogen production. No study to our knowledge, however, has examined the association between genetic variants and response to long-term vitamin E supplementation. We conducted a genome-wide association study (GWAS) of common variants associated with circulating α-tocopherol...
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