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Article

Amino-terminal extension present in the methionine aminopeptidase type 1c of Mycobacterium tuberculosis is indispensible for its activity.

BMC biochemistry - 5 Jul 2011

Kanudia Pavitra, Mittal Monica, Kumaran Sangaralingam, Chakraborti Pradip K

Abstract excerpt

BACKGROUND: Methionine aminopeptidase (MetAP) is a ubiquitous enzyme in both prokaryotes and eukaryotes, which catalyzes co-translational removal of N-terminal methionine from elongating polypeptide chains during protein synthesis. It specifically removes the terminal methionine in all organisms, if the penultimate residue is non-bulky and uncharged. The MetAP action for exclusion of N-terminal methionine is...

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Identifiers

PMID: 21729287
DOI: 10.1186/1471-2091-12-35
PMCID: PMC3154147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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