Article
Homology modeling and identification of amino acids involved in the catalytic process of Mycobacterium tuberculosis serine acetyltransferase.
Molecular medicine reports - 1 Mar 2017
Qiu Juanjuan, Zang Shizhu, Ma Yufang, Owusu Lawrence, Zhou Lei, Jiang Tao, Xin Yi
Abstract excerpt
Serine acetyltransferase (CysE) belongs to the hexapeptide acetyltransferase family and is involved in the biosynthesis of L‑cysteine in microorganisms. Mycobacterium tuberculosis CysE is regarded as a potential target for anti‑tuberculosis (TB) drugs; however, the structure and active sites of M. tuberculosis CysE remain unknown. The present study aimed to predict the secondary structure and to construct a 3D...
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