Article
Phenotypic expression of ADAMTS13 in glomerular endothelial cells.
PloS one - 1 Jan 2011
Tati Ramesh, Kristoffersson Ann-Charlotte, Ståhl Anne-Lie, Mörgelin Matthias, Motto David, Satchell Simon, Mathieson Peter, Manea-Hedström Minola, Karpman Diana
Abstract excerpt
BACKGROUND: ADAMTS13 is the physiological von Willebrand factor (VWF)-cleaving protease. The aim of this study was to examine ADAMTS13 expression in kidneys from ADAMTS13 wild-type (Adamts13⁺/⁺) and deficient (Adamts13⁻/⁻) mice and to investigate the expression pattern and bioactivity in human glomerular endothelial cells. METHODOLOGY/PRINCIPAL FINDINGS: Immunohistochemistry was performed on kidney sections from...
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