Article
Podocytes express ADAMTS13 in normal renal cortex and in patients with thrombotic thrombocytopenic purpura.
British journal of haematology - 1 Sept 2007
Manea Minola, Kristoffersson AnnCharlotte, Schneppenheim Reinhard, Saleem Moin A, Mathieson Peter W, Mörgelin Matthias, Björk Peter, Holmberg Lars, Karpman Diana
Abstract excerpt
Congenital thrombotic thrombocytopenic purpura (TTP) is associated with ADAMTS13 mutations. The major site of ADAMTS13 synthesis is the liver. Expression in other tissues, and in TTP, has not been shown. In this study, ADAMTS13 protein expression was investigated in normal kidney and in renal tis...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
