Article
A systematic review of replication studies of prostate cancer susceptibility genetic variants in high-risk men originally identified from genome-wide association studies.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2011
Ishak Miriam B, Giri Veda N
Abstract excerpt
BACKGROUND: Several prostate cancer genome-wide association studies (GWAS) have identified risk-associated genetic variants primarily in populations of European descent. Less is known about the association of these variants in high-risk populations, including men of African descent and men with a family history of prostate cancer. This article provides a detailed review of published studies of prostate...
Topics
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Male
- Polymorphism, Single Nucleotide
- Prostatic Neoplasms