Article
Validation of genome-wide prostate cancer associations in men of African descent.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2011
Chang Bao-Li, Spangler Elaine, Gallagher Stephen, Haiman Christopher A, Henderson Brian, Isaacs William, Benford Marnita L, Kidd LaCreis R, Cooney Kathleen, Strom Sara, Ingles Sue Ann, Stern Mariana C, Corral Roman, Joshi Amit D, Xu Jianfeng, Giri Veda N, Rybicki Benjamin, Neslund-Dudas Christine, Kibel Adam S, Thompson Ian M, Leach Robin J, Ostrander Elaine A, Stanford Janet L, Witte John, Casey Graham, Eeles Rosalind, Hsing Ann W, Chanock Stephen, Hu Jennifer J, John Esther M, Park Jong, Stefflova Klara, Zeigler-Johnson Charnita, Rebbeck Timothy R
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) have identified numerous prostate cancer susceptibility alleles, but these loci have been identified primarily in men of European descent. There is limited information about the role of these loci in men of African descent. METHODS: We identified 7,788 prostate cancer cases and controls with genotype data for 47 GWAS-identified loci. RESULTS: We identified...
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