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Article

Functional assessment of a promoter polymorphism in S100B, a putative risk variant for bipolar disorder.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Sept 2011

Dagdan Elif, Morris Derek W, Campbell Matthew, Hill Matthew, Rothermundt Matthias, Kästner Florian, Hohoff Christa, von Eiff Christof, Krakowitzky Petra, Gill Michael, McKeon Patrick, Roche Siobhan

Abstract excerpt

Calcium-binding protein S100B has been implicated in the pathology of bipolar affective disorder (BPAD) and schizophrenia (SZ). S100B protein levels are elevated in serum of patients with both disorders compared to controls. We previously reported genetic association of a SNP in the promoter of S100B, rs3788266, with a psychotic form of BPAD. To test for genotypic effects of rs3788266 in vivo, S100B serum protein...

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PMID: 21714070
DOI: 10.1002/ajmg.b.31211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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