Oligomerization of herpes simplex virus glycoprotein B occurs in the endoplasmic reticulum and a 102 amino acid cytosolic domain is dispensable for dimer assembly.

doi:10.1016/0042-6822(90)90359-y

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Article

Oligomerization of herpes simplex virus glycoprotein B occurs in the endoplasmic reticulum and a 102 amino acid cytosolic domain is dispensable for dimer assembly.

Virology - 1 Oct 1990

Ali M A

Abstract excerpt

Glycoprotein B (gB) is an essential protein specified by herpes simplex virus and a major envelope component of the virions. It is known to assemble into noncovalently associated dimers. The aim of this study was to investigate the role of topogenic domains of gB in dimer assembly and the intrace...

Topics

Amino Acids
Cells, Cultured
Cloning, Molecular
Cytosol
Endoplasmic Reticulum
Gene Expression
Humans
Mutation
Protein Conformation
Simplexvirus
Viral Envelope Proteins

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