Article
Contribution of endocytic motifs in the cytoplasmic tail of herpes simplex virus type 1 glycoprotein B to virus replication and cell-cell fusion.
Journal of virology - 1 Dec 2007
Beitia Ortiz de Zarate Igor, Cantero-Aguilar Lilia, Longo Magalie, Berlioz-Torrent Clarisse, Rozenberg Flore
Abstract excerpt
The use of endocytic pathways by viral glycoproteins is thought to play various functions during viral infection. We previously showed in transfection assays that herpes simplex virus type 1 (HSV-1) glycoprotein B (gB) is transported from the cell surface back to the trans-Golgi network (TGN) and that two motifs of gB cytoplasmic tail, YTQV and LL, function distinctly in this process. To investigate the role of...
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