Article
Herpes simplex virus type 1 glycoprotein B requires a cysteine residue at position 633 for folding, processing, and incorporation into mature infectious virus particles.
Journal of virology - 1 Jun 1998
Laquerre S, Anderson D B, Argnani R, Glorioso J C
Abstract excerpt
Herpes simplex virus type 1 (HSV-1) glycoprotein B (gB) resides in the virus envelope in an oligomeric form and plays an essential role in virus entry into susceptible host cells. The oligomerizing domain is a movable element consisting of amino acids 626 to 653 in the gB external domain. This do...
Topics
- Animals
- Chlorocebus aethiops
- Cysteine
- Endoplasmic Reticulum Chaperone BiP
- Herpesvirus 1, Human
- Mutation
- Protein Folding
- Vero Cells
- Viral Envelope Proteins
- Virion
- Virus Assembly