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Article

Interaction of Pestiviral E1 and E2 Sequences in Dimer Formation and Intracellular Retention.

International journal of molecular sciences - 6 Jul 2021

Mu Yu, Tews Birke Andrea, Luttermann Christine, Meyers Gregor

Abstract excerpt

Pestiviruses contain three envelope proteins: Erns, E1, and E2. Expression of HA-tagged E1 or mutants thereof showed that E1 forms homodimers and -trimers. C123 and, to a lesser extent, C171, affected the oligomerization of E1 with a double mutant C123S/C171S preventing oligomerization completely. E1 also establishes disulfide linked heterodimers with E2, which are crucial for the recovery of infectious viruses....

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Identifiers

PMID: 34298900
DOI: 10.3390/ijms22147285
PMCID: PMC8306095

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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