Article
Characterization of EBV gB indicates properties of both class I and class II viral fusion proteins.
Virology - 10 Nov 2007
Backovic Marija, Leser George P, Lamb Robert A, Longnecker Richard, Jardetzky Theodore S
Abstract excerpt
To gain insight into Epstein-Barr virus (EBV) glycoprotein B (gB), recombinant, secreted variants were generated. The role of putative transmembrane regions, the proteolytic processing and the oligomerization state of the gB variants were investigated. Constructs containing 2 of 3 C-terminal hydrophobic regions were secreted, indicating that these do not act as transmembrane anchors. The efficiency of cleavage of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
