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Article

A mutation degree model for the identification of transcriptional regulatory elements.

BMC bioinformatics - 27 Jun 2011

Zhang Changqing, Wang Jin, Hua Xu, Fang Jinggui, Zhu Huaiqiu, Gao Xiang

Abstract excerpt

BACKGROUND: Current approaches for identifying transcriptional regulatory elements are mainly via the combination of two properties, the evolutionary conservation and the overrepresentation of functional elements in the promoters of co-regulated genes. Despite the development of many motif detection algorithms, the discovery of conserved motifs in a wide range of phylogenetically related promoters is still a...

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PMID: 21708002
DOI: 10.1186/1471-2105-12-262
PMCID: PMC3228546

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