Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic silencing of MIR203 in multiple myeloma

28 Jun 2011

Abstract excerpt

Epigenetic inactivation of tumour suppressor microRNAs has been implicated in carcinogenesis. We studied the promoter methylation of MIR203 in eight normal marrow controls, eight multiple myeloma (MM) cell lines, 20 monoclonal gammopathy of undetermined significance (MGUS), 123 diagnostic MM and 19 relapsed MM samples by methylation-specific polymerase chain reaction. Promoter of MIR203 was unmethylated in normal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Histone Deacetylase Inhibitors Research
Share to MicroRNA in disease regulation
Share to Multiple Myeloma Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21707582
DOI: 10.1111/j.1365-2141.2011.08782.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Epigenetic silencing of MIR203 in multiple myelomaPMID 21707582Read ↗

Infrequent DNA methylation of miR-9-1 and miR-9-3 in multiple myeloma.Semantic proximity Read ↗

miR-23b/SP1/c-myc forms a feed-forward loop supporting multiple myeloma cell growthSemantic proximity Read ↗

Epigenetic inactivation of the MIR34B/C in multiple myelomaSemantic proximity Read ↗

Genome-wide pharmacologic unmasking identifies tumor suppressive microRNAs in multiple myeloma.Semantic proximity Read ↗

The microRNA miR-19a-3p suppresses cell growth, migration, and invasion in multiple myeloma via the Wnt/β-catenin pathwaySemantic proximity Read ↗

miR-203, a Tumor Suppressor Frequently Down-regulated by Promoter Hypermethylation in RhabdomyosarcomaSemantic proximity Read ↗

Complexity of miR-223 regulation by CEBPA in human AML.Semantic proximity Read ↗

Validation of ZAP-70 methylation and its relative significance in predicting outcome in chronic lymphocytic leukemiaSemantic proximity Read ↗

Aberrant promoter methylation of <i>insulin‐like growth factor binding protein‐3</i> gene in human cancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.