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Article

Genetic architecture and lifetime dynamics of inbreeding depression in a wild mammal.

Nature communications - 20 May 2021

Stoffel M A, Johnston S E, Pilkington J G, Pemberton J M

Abstract excerpt

Inbreeding depression is ubiquitous, but we still know little about its genetic architecture and precise effects in wild populations. Here, we combine long-term life-history data with 417 K imputed SNP genotypes for 5952 wild Soay sheep to explore inbreeding depression on a key fitness component, annual survival. Inbreeding manifests in long runs of homozygosity (ROH), which make up nearly half of the genome in...

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Identifiers

PMID: 34016997
DOI: 10.1038/s41467-021-23222-9
PMCID: PMC8138023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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