An evaluation of inbreeding measures using a whole-genome sequenced cattle pedigree.

doi:10.1038/s41437-020-00383-9

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Article

An evaluation of inbreeding measures using a whole-genome sequenced cattle pedigree.

Heredity - 1 Mar 2021

Alemu Setegn Worku, Kadri Naveen Kumar, Harland Chad, Faux Pierre, Charlier Carole, Caballero Armando, Druet Tom

Abstract excerpt

The estimation of the inbreeding coefficient (F) is essential for the study of inbreeding depression (ID) or for the management of populations under conservation. Several methods have been proposed to estimate the realized F using genetic markers, but it remains unclear which one should be used. Here we used whole-genome sequence data for 245 individuals from a Holstein cattle pedigree to empirically evaluate...

Topics

Alleles
Animals
Cattle
Genotype
Homozygote
Inbreeding
Pedigree
Polymorphism, Single Nucleotide

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Identifiers

PMID: 33159183
DOI: 10.1038/s41437-020-00383-9
PMCID: PMC8027009

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